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Used in low doses, the pure opiod antagonist Naltrexone (LDN refers to low-dose Naltrexone), a mainstay for treating opiate and alcohol addiction since 1984, has been reported to provide significant benefits for patients with autoimmune diseases, HIV infection, various cancers, and neurodegenerative diseases. The use of LDN in treating patients with multiple sclerosis (MS) was first proposed in the mid-1980s by Dr. Bernard Bihari, a New York City neurologist. In his clinical practice, the Harvard educated Bihari found that a low dose of naltrexone (1.5 to 4.5 mg daily) taken at bedtime offered benefits to patients with MS and other autoimmune conditions including rheumatoid arthritis and systemic lupus erythematosus. Since, additional studies and anecdotal reports have confirmed Bihari's findings and demonstrated the effectiveness of naltrexone for Crohn's disease, Parkinson's disease and other conditions.
LDN Cures Crohn's Disease
A recent publication in the Jan 2007 Journal of Gasteroenterology on the use of LDN in Crohn's Disease, was the first breakthrough publication to appear entitled, Low-Dose Naltrexone Therapy Improves Active Crohn's Disease by Jill Smith MD.
Crohn's disease is a severe inflammatory condition of the small bowel which can be difficult to treat. Not difficult for LDN however. Jill Smith, M.D. reported that two-thirds of her 17 Crohn's patients went into remission, and 90% of the group had some benefit. Her article showed impressive colonoscopy photos before and after LDN treatment with complete clearing of the inflammatory changes in the bowel mucosa. Dr. Smith concluded that "LDN therapy appears effective and safe in subjects with active Crohn's disease."(2)
Other Conditions Which Benefit from LDN
The major therapeutic action of LDN is the restoration of normal endorphin production by the brain. This is beneficial for any condition in which there is a deficiency in endorphin production, such as autoimmune disease, cancer and HIV/AIDS. Bernard Bihari, MD, who discovered the LDN protocol has used it in hundred of patients in the following categories:
LDN for Cancer
LDN is useful for cancers of the Bladder, Breast, Colon & Rectal Cancer , Glioblastoma, Lung Cancer (Non-Small Cell), Lymphocytic Leukemia (chronic), Lymphoma Hodgkin's and Non-Hodgkin's) Malignant Melanoma, Multiple Myeloma , Ovarian Cancer , Pancreatic Cancer, Prostate Cancer (untreated), Renal Cell Carcinoma, Uterine Cancer,
LDN is useful for Autoimmune and other Diseases:
LDN treatment has benefited these diseases: ALS (Lou Gehrig's Disease), Autism Spectrum Disorders, Chronic Fatigue Syndrome, Crohn's Disease, Fibromyalgia, HIV/AIDS, Multiple Sclerosis (MS), Parkinson's Disease, Psoriasis, Rheumatoid Arthritis, Scleroderma, Systemic Lupus (SLE), Ulcerative Colitis, Wegener's Granulomatosis
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